Evolving Ideas about Cyclins

  title={Evolving Ideas about Cyclins},
  author={James M Roberts},
instance, is associated primarily with activation of S James M. Roberts Division of Basic Sciences phase whereas CDK1 primarily with mitosis. However, assays using defined peptides reveal only subtle differFred Hutchinson Cancer Research Center and Howard Hughes Medical Institute ences in substrate preference between CDK1 and CDK2 (Holmes and Solomon, 1996), and there is no compelling 1100 Fairview Avenue North Seattle, Washington 98104 evidence that CDK2 and CDK1 are intrinsically different… CONTINUE READING


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