Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes

@article{Ramrath2018EvolutionaryST,
  title={Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes},
  author={D.J.F. Ramrath and M. Niemann and M. Leibundgut and P. Bieri and C. Prange and E. Horn and A. Leitner and D. Boehringer and A. Schneider and N. Ban},
  journal={Science},
  year={2018},
  volume={362}
}
Structure of the largest, most complex ribosome Ribosomes are two-subunit ribonucleoprotein assemblies that catalyze the translation of messenger RNA into protein. Ribosomal RNAs (rRNAs) play key structural and functional roles. Ramrath et al. report the high-resolution structure of mitochondrial ribosomes from the unicellular parasite Trypanosoma brucei that contain the smallest known rRNAs. The trypanosomal mitoribosome is the most complex ribosomal assembly characterized, with two rRNAs and… Expand
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