Evolutionary relationships of major histocompatibility complex class I genes in simian primates.

  title={Evolutionary relationships of major histocompatibility complex class I genes in simian primates.},
  author={Hiromi Sawai and Yoshi Kawamoto and Naoyuki Takahata and Yoko Satta},
  volume={166 4},
New World monkeys (NWMs) occupy a critical phylogenetic position in elucidating the evolutionary process of major histocompatibility complex (MHC) class I genes in primates. From three subfamilies of Aotinae, Cebinae, and Atelinae, the 5'-flanking regions of 18 class I genes are obtained and phylogenetically examined in terms of Alu/LINE insertion elements as well as the nucleotide substitutions. Two pairs of genes from Aotinae and Atelinae are clearly orthologous to human leukocyte antigen… CONTINUE READING
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