Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

@article{Boni2020EvolutionaryOO,
  title={Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic},
  author={M. F. Boni and Philippe Lemey and Xiaowei Jiang and Tommy T-Y Lam and Blair W. Perry and T. Castoe and Andrew Rambaut and D. Robertson},
  journal={Nature Microbiology},
  year={2020},
  pages={1 - 10}
}
  • M. F. Boni, Philippe Lemey, +5 authors D. Robertson
  • Published 2020
  • Medicine
  • Nature Microbiology
  • There are outstanding evolutionary questions on the recent emergence of human coronavirus SARS-CoV-2 including the role of reservoir species, the role of recombination and its time of divergence from animal viruses. We find that the sarbecoviruses—the viral subgenus containing SARS-CoV and SARS-CoV-2—undergo frequent recombination and exhibit spatially structured genetic diversity on a regional scale in China. SARS-CoV-2 itself is not a recombinant of any sarbecoviruses detected to date, and… CONTINUE READING

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