Evolutionary origin and divergence of GnIH and its homologous peptides.

Abstract

Probing undiscovered hypothalamic neuropeptides that play important roles in the regulation of pituitary function in vertebrates is essential for the progress of neuroendocrinology. In 2000, we discovered a novel hypothalamic dodecapeptide inhibiting gonadotropin release in quail and termed it gonadotropin-inhibitory hormone (GnIH). GnIH acts on the… (More)
DOI: 10.1016/j.ygcen.2008.10.002

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