Evolutionary history and mechanism of the Drosophila Cecropin gene family

@article{Date1998EvolutionaryHA,
  title={Evolutionary history and mechanism of the Drosophila Cecropin gene family},
  author={Atsuko Date and Yoko Satta and Naoyuki Takahata and Sadao I. Chigusa},
  journal={Immunogenetics},
  year={1998},
  volume={47},
  pages={417-429}
}
 Upon bacterial infection, insects secrete a set of synthesized antibacterial proteins into the hemolymph and initiate synergistic destruction of invaders. Cecropin is one such antibacterial protein which is also found in vertebrates. To study the evolutionary history and mechanism of the Cecropin gene family, we determined DNA sequences of one isogenic In(3R)C and six isofemale lines of Drosophila melanogaster as well as one line of D. simulans and of D. yakuba. The phylogenetic analysis of… CONTINUE READING

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