Evolutionary history and epigenetic regulation of the three paralogous pax7 genes in rainbow trout

@article{Seiliez2014EvolutionaryHA,
  title={Evolutionary history and epigenetic regulation of the three paralogous pax7 genes in rainbow trout},
  author={Iban Seiliez and Jacob Michael Froehlich and Lucie Marandel and Jean-Charles Gabillard and Peggy R Biga},
  journal={Cell and Tissue Research},
  year={2014},
  volume={359},
  pages={715-727}
}
The extraordinary muscle growth potential of teleost fish, particular those of the Salmoninae clade, elicits questions about the regulation of the relatively highly conserved transcription factors of the myogenic program. The pseudotetraploid nature of the salmonid genome adds another layer of regulatory complexity that must be reconciled with epigenetic data to improve our understanding of the achievement of lifelong muscle growth in these fish. We identify three paralogous pax7 genes (pax7a1… CONTINUE READING