Evolutionary genomics in Metazoa: the mitochondrial DNA as a model system.

@article{Saccone1999EvolutionaryGI,
  title={Evolutionary genomics in Metazoa: the mitochondrial DNA as a model system.},
  author={Cecilia Saccone and Carla De Giorgi and Carmela Gissi and Graziano Pesole and Aurelio Reyes},
  journal={Gene},
  year={1999},
  volume={238 1},
  pages={195-209}
}
One of the most important aspects of mitochondrial (mt) genome evolution in Metazoa is constancy of size and gene content of mtDNA, whose plasticity is maintained through a great variety of gene rearrangements probably mediated by tRNA genes. The trend of mtDNA to maintain the same genetic structure within a phylum (e.g., Chordata) is generally accepted, although more recent reports show that a considerable number of transpositions are observed also between closely related organisms. Base… CONTINUE READING
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