Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion.

@article{Basanta2008EvolutionaryGT,
  title={Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion.},
  author={David Basanta and Matthias Simon and Haralambos Hatzikirou and A. Deutsch},
  journal={Cell proliferation},
  year={2008},
  volume={41 6},
  pages={
          980-987
        }
}
OBJECTIVES Tumour progression has been described as a sequence of traits or phenotypes that cells have to acquire if the neoplasm is to become an invasive and malignant cancer. Although genetic mutations that lead to these phenotypes are random, the process by which some of these mutations become successful and cells spread is influenced by tumour microenvironment and the presence of other cell phenotypes. It is thus likely that some phenotypes that are essential in tumour progression will… CONTINUE READING

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