Evolutionary forward genomics reveals novel insights into the genes and pathways dysregulated in recurrent early pregnancy loss.

Abstract

STUDY QUESTION Are the genes that gained novel expression in the endometria of Eutherian (placental) mammals more likely to be dysregulated in patients with endometrial-associated recurrent early pregnancy loss (REPL)? SUMMARY ANSWER There was a significant enrichment of genes dysregulated in REPL patients among the Eutherian-specific endometrial genes… (More)
DOI: 10.1093/humrep/deu355

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