Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.

  title={Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes.},
  author={Robert M. Waterhouse and Evgenia V. Kriventseva and Stephan Meister and Zhiyong Xi and Kanwal S. Alvarez and Lyric C. Bartholomay and Carolina Barillas-Mury and Guowu Bian and St{\'e}phanie A. Blandin and Bruce M. Christensen and Yuemei Dong and Haobo Jiang and Michael R. Kanost and Anastasios C Koutsos and Elena A Levashina and Jianyong Li and Petros Ligoxygakis and Robert M. MacCallum and George F. Mayhew and A Mendes and Kristin Michel and Mike A Osta and Susan M. Paskewitz and Sang Woon Shin and Dina Vlachou and Lihui Wang and Weiqi Wei and Liangbiao Zheng and Zhen Zou and David W. Severson and Alexander S. Raikhel and Fotis C. Kafatos and George Dimopoulos and Evgeny M. Zdobnov and George K. Christophides},
  volume={316 5832},
Mosquitoes are vectors of parasitic and viral diseases of immense importance for public health. The acquisition of the genome sequence of the yellow fever and Dengue vector, Aedes aegypti (Aa), has enabled a comparative phylogenomic analysis of the insect immune repertoire: in Aa, the malaria vector Anopheles gambiae (Ag), and the fruit fly Drosophila melanogaster (Dm). Analysis of immune signaling pathways and response modules reveals both conservative and rapidly evolving features associated… CONTINUE READING
Highly Influential
This paper has highly influenced 28 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 234 extracted citations

[Progress in innate immunity-related genes in insects].

Yi chuan = Hereditas • 2018
View 9 Excerpts
Highly Influenced

Evolutionary genetics of insect innate immunity

Briefings in functional genomics • 2015
View 5 Excerpts
Highly Influenced

Evolutionary genomics of Glossina morsitans immune-related CLIP domain serine proteases and serine protease inhibitors.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases • 2011
View 4 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-9 of 9 references

Immunity 2006;24:463

A Zaidman-Remy

Insect Biochem

O. Andreev, L. Shi
Mol . Biol . • 2006

PLoS Pathog 2006;2:e14

V Bischoff

PLoS Pathog 2006;2:e52

Y Dong

Immunity 2005;23:65

LF Moita

Trends Parasitol 2005;21:192

BM Christensen

Leukocyte Biol 2004;75:18

JL Imler, L J.Zheng

Cell 2001;104:709

EA Levashina

Cell 2006;127:1425

M Gottar

Similar Papers

Loading similar papers…