Evolutionary dynamics of complex networks of HIV drug-resistant strains: the case of San Francisco.

@article{Smith2010EvolutionaryDO,
  title={Evolutionary dynamics of complex networks of HIV drug-resistant strains: the case of San Francisco.},
  author={Robert J. Smith and Justin T Okano and James S. Kahn and Erin N. Bodine and Sally M. Blower},
  journal={Science},
  year={2010},
  volume={327 5966},
  pages={697-701}
}
Over the past two decades, HIV resistance to antiretroviral drugs (ARVs) has risen to high levels in the wealthier countries of the world, which are able to afford widespread treatment. We have gained insights into the evolution and transmission dynamics of ARV resistance by designing a biologically complex multistrain network model. With this model, we traced the evolutionary history of ARV resistance in San Francisco and predict its future dynamics. By using classification and regression… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
Showing 1-10 of 53 extracted citations

Geolocalization of HIV-1 subtypes and resistance mutations of patients failing antiretroviral therapy in Salvador - Brazil.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases • 2017

Towards Optimal Control of Evolutionary Games on Networks

IEEE Transactions on Automatic Control • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Antivir Ther

S C Orrell
Antivir Ther • 2009

Indian J Med Microbiol

S A J Kandathil
Indian J Med Microbiol • 2009

Indian J. Med. Microbiol

A J Kandathil
Indian J. Med. Microbiol • 2009

Lancet

R M Granich, C F Gilks, +3 authors Williams
Lancet • 2009

AIDS Res Hum Retroviruses

S V Pillay
AIDS Res Hum Retroviruses • 2008

AIDS Res. Hum. Retroviruses

L Ross, N Parkin, R Lanier
AIDS Res. Hum. Retroviruses • 2008

Arch Virol

S A Jlizi
Arch Virol • 2008

Clin Infect Dis

S M S Hirsch
Clin Infect Dis • 2008

PLoS Med

S J A Johnson
PLoS Med • 2008

Virus Res

J Martinez-Picado, M A Martínez
Virus Res • 2008

Similar Papers

Loading similar papers…