Evolutionary dynamics of bovine coronaviruses: natural selection pattern of the spike gene implies adaptive evolution of the strains.

  title={Evolutionary dynamics of bovine coronaviruses: natural selection pattern of the spike gene implies adaptive evolution of the strains.},
  author={Mehdi R. M. Bidokhti and Madeleine Tr{\aa}v{\'e}n and Neel K Krishna and Muhammad Munir and S{\'a}ndor Bel{\'a}k and Stefan Alenius and Mart{\'i} Cortey},
  journal={The Journal of general virology},
  volume={94 Pt 9},
Coronaviruses demonstrate great potential for interspecies transmission, including zoonotic outbreaks. Although bovine coronavirus (BCoV) strains are frequently circulating in cattle farms worldwide, causing both enteric and respiratory disease, little is known about their genomic evolution. We sequenced and analysed the full-length spike (S) protein gene of 33 BCoV strains from dairy and feedlot farms collected during outbreaks that occurred from 2002 to 2010 in Sweden and Denmark. Amino acid… 

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