Evolutionary divergence and limits of conserved non-coding sequence detection in plant genomes

  title={Evolutionary divergence and limits of conserved non-coding sequence detection in plant genomes},
  author={Anna R. Reineke and Erich Bornberg-Bauer and Jenny Gu},
  booktitle={Nucleic acids research},
The discovery of regulatory motifs embedded in upstream regions of plants is a particularly challenging bioinformatics task. Previous studies have shown that motifs in plants are short compared with those found in vertebrates. Furthermore, plant genomes have undergone several diversification mechanisms such as genome duplication events which impact the evolution of regulatory motifs. In this article, a systematic phylogenomic comparison of upstream regions is conducted to further identify… CONTINUE READING
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