Evolutionary conservation of histone modifications in mammals.

@article{Woo2012EvolutionaryCO,
  title={Evolutionary conservation of histone modifications in mammals.},
  author={Yong H Woo and Wen-Hsiung Li},
  journal={Molecular biology and evolution},
  year={2012},
  volume={29 7},
  pages={1757-67}
}
Histone modification is an important mechanism of gene regulation in eukaryotes. Why many histone modifications can be stably maintained in the midst of genetic and environmental changes is a fundamental question in evolutionary biology. We obtained genome-wide profiles of three histone marks, H3 lysine 4 tri-methylation (H3K4me3), H3 lysine 4 mono-methylation (H3K4me1), and H3 lysine 27 acetylation (H3K27ac), for several cell types from human and mouse. We identified histone modifications that… CONTINUE READING
Highly Cited
This paper has 38 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
18 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…