Evolutionary and functional diversity of the Pseudomonas type IVa pilin island.

@article{Giltner2011EvolutionaryAF,
  title={Evolutionary and functional diversity of the Pseudomonas type IVa pilin island.},
  author={Carmen L. Giltner and Navpreet Rana and Michael N Lunardo and Anne Q Hussain and Lori L Burrows},
  journal={Environmental microbiology},
  year={2011},
  volume={13 1},
  pages={250-264}
}
In Pseudomonas aeruginosa, most proteins involved in type IVa pilus (T4aP) biogenesis are highly conserved except for the major pilin PilA and the minor pilins involved in pilus assembly. Here we show that each of the five major pilin alleles is associated with a specific set of minor pilins, and unrelated strains with the same major pilin type have identical minor pilin genes. The sequences of the minor pilin genes of strains with group III and V pilins are identical, suggesting that these… CONTINUE READING