Evolutionary analysis reveals collective properties and specificity in the C‐type lectin and lectin‐like domain superfamily

@article{Ebner2003EvolutionaryAR,
  title={Evolutionary analysis reveals collective properties and specificity in the C‐type lectin and lectin‐like domain superfamily},
  author={Sharon Ebner and Nathan Sharon and Nir Ben-Tal},
  journal={Proteins: Structure},
  year={2003},
  volume={53}
}
Members of the C‐type lectin/C‐type lectin‐like domain (CTL/CTLD) superfamily share a common fold and are involved in a variety of functions, such as generalized defense mechanisms against foreign agents, discrimination between healthy and pathogen‐infected cells, and endocytosis and blood coagulation. In this work we used ConSurf, a computer program recently developed in our lab, to perform an evolutionary analysis of this superfamily in order to further identify characteristics of all or part… 

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