Evolutionary History of Sex-Linked Mammalian Amelogenin Genes

@article{Iwase2007EvolutionaryHO,
  title={Evolutionary History of Sex-Linked Mammalian Amelogenin Genes},
  author={Mineyo Iwase and Satoko Kaneko and Hielim Kim and Yoko Satta and Naoyuki Takahata},
  journal={Cells Tissues Organs},
  year={2007},
  volume={186},
  pages={49 - 59}
}
  • Mineyo Iwase, Satoko Kaneko, +2 authors Naoyuki Takahata
  • Published in Cells Tissues Organs 2007
  • Medicine, Biology
  • Amelogenin (AMEL) arose prior to the emergence of tetrapods and transposed into an intron of the Rho GTPase-activating protein 6 gene. In the mammalian lineage leading to eutherians, a pair of homologous autosomes with this nested gene structure fused with the then already differentiating sex chromosomes by suppressing homologous recombination. As sex-chromosomal differentiation extended to the fused region, a pair of homologous AMEL genes too differentiated from each other in two steps; first… CONTINUE READING

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