Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila.

@article{Swanson2001EvolutionaryEA,
  title={Evolutionary EST analysis identifies rapidly evolving male reproductive proteins in Drosophila.},
  author={Willie J. Swanson and Andrew G. Clark and Heidi M Waldrip-Dail and Mariana F Wolfner and Charles F. Aquadro},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 13},
  pages={7375-9}
}
Sequence comparisons of genomes or expressed sequence tags (ESTs) from related organisms provide insight into functional conservation and diversification. We compare the sequences of ESTs from the male accessory gland of Drosophila simulans to their orthologs in its close relative Drosophila melanogaster, and demonstrate rapid divergence of many of these reproductive genes. Nineteen ( approximately 11%) of 176 independent genes identified in the EST screen contain protein-coding regions with an… CONTINUE READING
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