Evolutionary Dynamics of the Interferon-Induced Transmembrane Gene Family in Vertebrates

@article{Zhang2012EvolutionaryDO,
  title={Evolutionary Dynamics of the Interferon-Induced Transmembrane Gene Family in Vertebrates},
  author={Z. Zhang and J. Liu and Meng Li and H. Yang and Chiyu Zhang},
  journal={PLoS ONE},
  year={2012},
  volume={7}
}
Vertebrate interferon-induced transmembrane (IFITM) genes have been demonstrated to have extensive and diverse functions, playing important roles in the evolution of vertebrates. Despite observance of their functionality, the evolutionary dynamics of this gene family are complex and currently unknown. Here, we performed detailed evolutionary analyses to unravel the evolutionary history of the vertebrate IFITM family. A total of 174 IFITM orthologous genes and 112 pseudogenes were identified… Expand
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