Evolutionary Changes on the Way to Clathrin-Mediated Endocytosis in Animals.

  title={Evolutionary Changes on the Way to Clathrin-Mediated Endocytosis in Animals.},
  author={Mykola Dergai and Anton V. Iershov and Olga Novokhatska and Serhii Pankivskyi and Alla V Rynditch},
  journal={Genome biology and evolution},
  volume={8 3},
Endocytic pathways constitute an evolutionarily ancient system that significantly contributed to the eukaryotic cell architecture and to the diversity of cell type-specific functions and signaling cascades, in particular of metazoans. Here we used comparative proteomic studies to analyze the universal internalization route in eukaryotes, clathrin-mediated endocytosis (CME), to address the issues of how this system evolved and what are its specific features. Among 35 proteins crucially required… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications referenced by this paper.
Showing 1-10 of 54 references

Crystal structure of the dynamin tetramer

  • X Robert, P Gouet
  • Nature
  • 2015

Endocytosis : past , present , and future

  • L Schrödinger
  • Cold Spring Harb Perspect Biol .
  • 2014

Pfam : the protein families database

  • A Gadeyne
  • Nucleic Acids Res .
  • 2014

Similar Papers

Loading similar papers…