Evolutionarily conserved organization of the dopaminergic system in lamprey: SNc/VTA afferent and efferent connectivity and D2 receptor expression.

@article{PrezFernndez2014EvolutionarilyCO,
  title={Evolutionarily conserved organization of the dopaminergic system in lamprey: SNc/VTA afferent and efferent connectivity and D2 receptor expression.},
  author={Juan P{\'e}rez-Fern{\'a}ndez and Marcus Stephenson-Jones and Shreyas M. Suryanarayana and Brita Robertson and Sten Grillner},
  journal={The Journal of comparative neurology},
  year={2014},
  volume={522 17},
  pages={3775-94}
}
The dopaminergic system influences motor behavior, signals reward and novelty, and is an essential component of the basal ganglia in all vertebrates including the lamprey, one of the phylogenetically oldest vertebrates. The intrinsic organization and function of the lamprey basal ganglia is highly conserved. For instance, the direct and indirect pathways are modulated through dopamine D1 and D2 receptors in lamprey and in mammals. The nucleus of the tuberculum posterior, a homologue of the… CONTINUE READING