Evolution of yellow Gene Regulation and Pigmentation in Drosophila

  title={Evolution of yellow Gene Regulation and Pigmentation in Drosophila},
  author={Patricia J Wittkopp and Kathy Vaccaro and Sean B. Carroll},
  journal={Current Biology},
BACKGROUND Changes in developmental gene expression are central to phenotypic evolution, but the genetic mechanisms underlying these changes are not well understood. Interspecific differences in gene expression can arise from evolutionary changes in cis-regulatory DNA and/or in the expression of trans-acting regulatory proteins, but few case studies have distinguished between these mechanisms. Here, we compare the regulation of the yellow gene, which is required for melanization, among… CONTINUE READING