Evolution of viviparity and the maternal immune system: Major histocompatibility complex (MHC) class I genes in skinks

Abstract

With the evolution of viviparity, the complex immune system of vertebrates has become a potential threat to the “semi-foreign” fetus. Mammalian embryos avoid immune rejection by altering placental expression of two types of major histocompatibility complex (MHC) genes, classical class I and non-classical class I genes. While non-classical class I genes are… (More)

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9 Figures and Tables