Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus.

@article{Li2009EvolutionOV,
  title={Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus.},
  author={Min Li and Binh An Diep and Amer E. Villaruz and Kevin R. Braughton and Xiaofei Jiang and Frank R Deleo and Henry F. Chambers and Yuan Lu and Michael Otto},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 14},
  pages={5883-8}
}
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has recently emerged worldwide. The United States, in particular, is experiencing a serious epidemic of CA-MRSA that is almost entirely caused by an extraordinarily infectious strain named USA300. However, the molecular determinants underlying the pathogenic success of CA-MRSA are mostly unknown. To gain insight into the evolution of the exceptional potential of USA300 to cause disease, we compared the phylogeny and… CONTINUE READING
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