Evolution of the tyrosinase related gene (TYRL) in primates.


Tyrosinase is the major enzyme responsible for the formation of melanin pigment and is found throughout the animal kingdom. In humans, the tyrosinase gene (TYR) maps to the long arm of chromosome 11 at band q14-->q21, while a tyrosinase related gene (TYRL) maps to the short arm of chromosome 11 at p11.2-->cen. We and others have found that the TYRL locus… (More)


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