Evolution of the type-1 (Th1)-type-2 (Th2) cytokine paradigm.

  • Daniel R. Lucey
  • Published 1999 in Infectious disease clinics of North America


During the past 12 years, since the discovery of murine Th1 and Th2 clones, increasing numbers of cells that make type-1 and type-2 cytokines have been recognized, and a growing number of these cytokines have been described. Emphasis has shifted from the CD4+ T cell, as the source of Th1-Th2 cytokines, to the functional effect of the type-1 and type-2… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.