Evolution of the molecular machines for protein import into mitochondria.

Abstract

In creating mitochondria some 2 billion years ago, the first eukaryotes needed to establish protein import machinery in the membranes of what was a bacterial endosymbiont. Some of the preexisting protein translocation apparatus of the endosymbiont appears to have been commandeered, including molecular chaperones, the signal peptidase, and some components of… (More)

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Cite this paper

@article{Doleal2006EvolutionOT, title={Evolution of the molecular machines for protein import into mitochondria.}, author={Pavel Dole{\vz}al and Vladimir A. Likic and Jan Tachez{\'y} and Trevor Lithgow}, journal={Science}, year={2006}, volume={313 5785}, pages={314-8} }