Evolution of the gonadotropin-releasing hormone (GnRH) gene family in relation to vertebrate tetraploidizations.

@article{Tostivint2011EvolutionOT,
  title={Evolution of the gonadotropin-releasing hormone (GnRH) gene family in relation to vertebrate tetraploidizations.},
  author={Herv{\'e} Tostivint},
  journal={General and comparative endocrinology},
  year={2011},
  volume={170 3},
  pages={575-81}
}
The neuropeptide gonadotropin-releasing hormone (GnRH) plays an important role in the control of reproductive functions. Vertebrates possess multiple GnRH isoforms that are classified into three main groups, namely GnRH1, GnRH2 and GnRH3. In the present study, we show that the chromosomal organization of the three GnRH loci is very well conserved among gnathostome species. We analyzed genes belonging to several other multigenic families that are present in the vicinity of GnRH genes. Five of… CONTINUE READING

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