Evolution of the genetic code

@article{Woese1965EvolutionOT,
  title={Evolution of the genetic code},
  author={Carl R. Woese},
  journal={The Science of Nature},
  year={1965},
  volume={60},
  pages={447-459}
}
The origin of the genetic code is not merely an evolutionary juggling of codon assignments until some optimal configuration is achieved. I t is, rather, the more interesting and profound problem of how codon assignments arose. This is part and parcel of the origin of a translating mechanism. A plausible scheme for the evolution of translation starting from a simple class of nucleic acid components is presented. Such an evolution may appear unique, idiosyncratic, when viewed only in terms of… CONTINUE READING
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