Evolution of the enterobacterial sulA gene: a component of the SOS system encoding an inhibitor of cell division.

@article{Freudl1987EvolutionOT,
  title={Evolution of the enterobacterial sulA gene: a component of the SOS system encoding an inhibitor of cell division.},
  author={Roland Freudl and Gabi Braun and Nadine Honor{\'e} and Stewart T Cole},
  journal={Gene},
  year={1987},
  volume={52 1},
  pages={31-40}
}
The LexA-regulated sulA (sfiA) gene of Escherichia coli encodes an unstable protein which inhibits cell division. By determining the nucleotide sequences of the corresponding genes from the related bacteria Salmonella typhimurium, Enterobacter aerogenes and Serratia marcescens it was found that the regulatory region and the LexA binding site (SOS box) have been better conserved during evolution than the coding sequence. The N terminus of the SulA protein [amino acid (aa) residues 1-30] has… CONTINUE READING