Evolution of the cellular stress proteome: from monophyletic origin to ubiquitous function

@article{Kltz2003EvolutionOT,
  title={Evolution of the cellular stress proteome: from monophyletic origin to ubiquitous function},
  author={D. K{\"u}ltz},
  journal={Journal of Experimental Biology},
  year={2003},
  volume={206},
  pages={3119 - 3124}
}
  • D. Kültz
  • Published 2003
  • Biology, Medicine
  • Journal of Experimental Biology
SUMMARY Cells respond to acute environmental change by activating a stress response that is widely studied. However, knowledge of this stress response is fragmentary, and a unifying concept explaining its universality for many different species and types of stress is lacking. The need for a holistic view emphasizing the key aspects of the stress response is addressed by the following hypothesis. The cellular stress response is a reaction to any form of macromolecular damage that exceeds a set… Expand
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