Evolution of the c-kit-positive cell response to pathological challenge in the myocardium.

@article{Fransioli2008EvolutionOT,
  title={Evolution of the c-kit-positive cell response to pathological challenge in the myocardium.},
  author={Jenna R Fransioli and Brandi Bailey and Natalie A. Gude and Christopher T. Cottage and John Muraski and Gregory N Emmanuel and Weitao Wu and Roberto L. Alvarez and Marta Rubio and Sergio Ottolenghi and Erik Schaefer and Mark A Sussman},
  journal={Stem cells},
  year={2008},
  volume={26 5},
  pages={1315-24}
}
Cumulative evidence indicates that myocardium responds to growth or injury by recruitment of stem and/or progenitor cells that participate in repair and regenerative processes. Unequivocal identification of this population has been hampered by lack of reagents or markers specific to the recruited population, leading to controversies regarding the nature of these cells. Use of a transgenic mouse expressing green fluorescent protein driven by the c-kit promoter allows for unambiguous… CONTINUE READING
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