Evolution of the arginine kinase gene family.

  title={Evolution of the arginine kinase gene family.},
  author={Kouji Uda and Naka Fujimoto and Youhei Akiyama and Kanae Mizuta and Kumiko Tanaka and W. Ross Ellington and Tomohiko Suzuki},
  journal={Comparative biochemistry and physiology. Part D, Genomics & proteomics},
  volume={1 2},
Arginine kinase (AK), catalyzing the reversible transfer of phosphate from MgATP to arginine yielding phosphoarginine and MgADP, is widely distributed throughout the invertebrates and is also present in certain protozoa. Typically, these proteins are found as monomers targeted to the cytoplasm, but true dimeric and contiguous dimeric AKs as well as mitochondrial AK activities have been observed. In the present study, we have obtained the sequences of the genes for AKs from two distantly related… CONTINUE READING
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