Evolution of the amino acid code: Inferences from mitochondrial codes

@article{Jukes1983EvolutionOT,
  title={Evolution of the amino acid code: Inferences from mitochondrial codes},
  author={Thomas H. Jukes},
  journal={Journal of Molecular Evolution},
  year={1983},
  volume={19},
  pages={219-225}
}
The amino acid code is usually presented as a table of 64 codons. Actually the code results from the action of tRNA molecules that carry amino acids to codons in mRNA by means of codon-anticodon pairing. The tRNA molecules are transcribed from genes that undergo evolution and the number of anticodons can therefore increase during evolution, but the number of codons is fixed at 64. Mammalian mitochondrial codes contain only 22 anticodons for 20 amino acids as compared with 54 anticodons for 20… CONTINUE READING

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