Evolution of the Neurohypophysial Hormones, with Reference to Amphibians


THE neurohypophysial hormones of two European species of amphibians, the frog Rana esculenta1,2 and the toad Bufo bufo3, have been chemically identified. One of these, vasotocin (Arg8-oxytocin), is identical to the hormone found in birds4 or in bony fish5–7. The other, mesotocin (Ile8-oxytocin), has a structure intermediate between that of isotocin (Ser4… (More)
DOI: 10.1038/221759a0


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