Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities.

@article{Tang2009EvolutionOT,
  title={Evolution of the Drosophila nuclear pore complex results in multiple hybrid incompatibilities.},
  author={Shanwu Tang and Daven C Presgraves},
  journal={Science},
  year={2009},
  volume={323 5915},
  pages={779-82}
}
Speciation often involves the evolution of incompatible gene interactions that cause sterility or lethality in hybrids between populations. These so-called hybrid incompatibilities occur between two or more functionally divergent loci. We show that the nucleoporin 160kDa (Nup160) gene of the fruitfly Drosophila simulans is incompatible with one or more factors on the D. melanogaster X chromosome, causing hybrid lethality. Nup160 encodes a nuclear pore complex protein and shows evidence of… CONTINUE READING

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