Evolution of structural fitness and multifunctional aspects of mycobacterial RND family transporters
@article{Sandhu2017EvolutionOS, title={Evolution of structural fitness and multifunctional aspects of mycobacterial RND family transporters}, author={Padmani Sandhu and Yusuf Akhter}, journal={Archives of Microbiology}, year={2017}, volume={200}, pages={19-31} }
Drug resistance is a major concern due to the evolution and emergence of pathogenic bacterial strains with novel strategies to resist the antibiotics in use. Mycobacterium tuberculosis (Mtb) is one of such pathogens with reported strains, which are not treatable with any of the available anti-TB drugs. This scenario has led to the need to look for some novel drug targets in Mtb, which may be exploited to design effective treatment strategies against the infection. The goal of this review is to…
11 Citations
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