Evolution of selenium utilization traits

  title={Evolution of selenium utilization traits},
  author={H{\'e}ctor Romero and Yan Zhang and Vadim N. Gladyshev and Gustavo Salinas},
  journal={Genome Biology},
  pages={R66 - R66}
The essential trace element selenium is used in a wide variety of biological processes. Selenocysteine (Sec), the 21st amino acid, is co-translationally incorporated into a restricted set of proteins. It is encoded by an UGA codon with the help of tRNASec (SelC), Sec-specific elongation factor (SelB) and a cis-acting mRNA structure (SECIS element). In addition, Sec synthase (SelA) and selenophosphate synthetase (SelD) are involved in the biosynthesis of Sec on the tRNASec. Selenium is also… CONTINUE READING