Evolution of primate gene expression: drift and corrective sweeps?

  title={Evolution of primate gene expression: drift and corrective sweeps?},
  author={R Chaix and Mehmet Somel and David P. Kreil and Philipp Khaitovich and Gerton Lunter},
  volume={180 3},
Changes in gene expression play an important role in species' evolution. Earlier studies uncovered evidence that the effect of mutations on expression levels within the primate order is skewed, with many small downregulations balanced by fewer but larger upregulations. In addition, brain-expressed genes appeared to show an increased rate of evolution on the branch leading to human. However, the lack of a mathematical model adequately describing the evolution of gene expression precluded the… CONTINUE READING
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