Evolution of primate α and θ defensins revealed by analysis of genomes

  title={Evolution of primate α and θ defensins revealed by analysis of genomes},
  author={Diyan Li and Long Zhang and H. Yin and Huailiang Xu and J. Trask and D. G. Smith and Y. Li and M. Yang and Q. Zhu},
  journal={Molecular Biology Reports},
  • Diyan Li, Long Zhang, +6 authors Q. Zhu
  • Published 2014
  • Biology, Medicine
  • Molecular Biology Reports
  • Abstract Defensins are endogenous peptides with cysteine-rich antimicrobial ability that contribute to host defence against bacterial, fungal and viral infections. There are three subfamilies of defensins in primates: α, β and θ-defensins. α-defensins are most present in neutrophils and Paneth cells; β-defensins are involved in protecting the skin and the mucous membranes of the respiratory, genitourinary and gastrointestinal tracts; and θ-defensins are physically distinguished as the only… CONTINUE READING
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