Evolution of mutation rates in bacteria

@article{Denamur2006EvolutionOM,
  title={Evolution of mutation rates in bacteria},
  author={Erick Denamur and Ivan Matic},
  journal={Molecular Microbiology},
  year={2006},
  volume={60}
}
Evolutionary success of bacteria relies on the constant fine‐tuning of their mutation rates, which optimizes their adaptability to constantly changing environmental conditions. When adaptation is limited by the mutation supply rate, under some conditions, natural selection favours increased mutation rates by acting on allelic variation of the genetic systems that control fidelity of DNA replication and repair. Mutator alleles are carried to high frequency through hitchhiking with the adaptive… 

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