Evolution of modular intraflagellar transport from a coatomer-like progenitor

@article{vanDam2013EvolutionOM,
  title={Evolution of modular intraflagellar transport from a coatomer-like progenitor},
  author={Teunis J. P. van Dam and Matthew J Townsend and Martina Furdek Turk and Avner Schlessinger and Andrej Sali and Mark C. Field and Martijn A. Huynen},
  journal={Proceedings of the National Academy of Sciences},
  year={2013},
  volume={110},
  pages={6943 - 6948}
}
The intraflagellar transport (IFT) complex is an integral component of the cilium, a quintessential organelle of the eukaryotic cell. The IFT system consists of three subcomplexes [i.e., intraflagellar transport (IFT)-A, IFT-B, and the BBSome], which together transport proteins and other molecules along the cilium. IFT dysfunction results in diseases collectively called ciliopathies. It has been proposed that the IFT complexes originated from vesicle coats similar to coat protein complex (COP… 

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Manuscript submitted to eLife
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