Evolution of macromolecular import pathways in mitochondria, hydrogenosomes and mitosomes

  title={Evolution of macromolecular import pathways in mitochondria, hydrogenosomes and mitosomes},
  author={Trevor J Lithgow and Andr{\'e} Schneider},
  journal={Philosophical Transactions of the Royal Society B: Biological Sciences},
  pages={799 - 817}
  • T. Lithgow, A. Schneider
  • Published 12 March 2010
  • Biology
  • Philosophical Transactions of the Royal Society B: Biological Sciences
All eukaryotes require mitochondria for survival and growth. The origin of mitochondria can be traced down to a single endosymbiotic event between two probably prokaryotic organisms. Subsequent evolution has left mitochondria a collection of heterogeneous organelle variants. Most of these variants have retained their own genome and translation system. In hydrogenosomes and mitosomes, however, the entire genome was lost. All types of mitochondria import most of their proteome from the cytosol… 

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