Evolution of liver transplantation in Europe: Report of the European Liver Transplant Registry

  title={Evolution of liver transplantation in Europe: Report of the European Liver Transplant Registry},
  author={Ren{\'e} Adam and Paul Mcmaster and John G O'grady and Denis Castaing and J{\"u}rgen Klempnauer and Neville V. Jamieson and Peter Neuhaus and Jan Lerut and Mauro Salizzoni and Stephen G. Pollard and Ferdinand Muhlbacher and Xavier Rogiers and Juan Carlos Garcia Valdecasas and Joaqu{\'i}n Berenguer and Daniel Jaeck and Enrique Moreno Gonz{\'a}lez},
  journal={Liver Transplantation},
The European Liver Transplant Registry (ELTR) currently allows for the analysis of 44,286 liver transplantations (LTs) performed on 39,196 patients in a 13‐year period. After an exponential increase, the number of LTs is plateauing due to a lack of organs. To cope with this, alternatives to cadaveric LT, such as split LT, domino LT, or living‐related LT (LRLT) are being used increasingly. They now account for 11% of all procedures. One of the most important findings in the evolution of LT is… 
Survival Outcomes in Liver Transplantation With Elderly Donors: Analysis of Andalusian Transplant Register.
Use of elderly donors is a safe strategy to reduce the scarcity of donors, provided that a D-MELD score below 1500 is obtained, and retransplant rates increase progressively with donor age.
Results of liver transplants from donors aged 70 plus: analysis of Andalusian transplant register.
Although re-transplantation rates increase progressively with donor age, they remain less than 10%.
Split and living donor liver transplantation
To summarize, currently, adult living donor liver transplantation has the same probability of survival at 1 and 5 years when compared to deceased donor liver transplants.
Trends and experiences in liver retransplantation over 15 years
Apart from the changing indications for re‐LT with an increasing amount of initial organ failure and hepatic artery thrombosis, the analysis showed a decreasing amount of complications such as rejection, ischemic type biliary lesions, and recurrence of the disease with unchanged outcome over a period of 15 years.
Evolution of Liver Transplantation Program in Shiraz, Iran
LT is now an affordable treatment for patients with ESLD in Iran with acceptable survival, which has further been improved in recent years.
Living Donor Liver Transplantation in Japan
It is important that cadaveric donor liver transplant is promoted in addition to LDLT in Japan because of the number of patients requiring transplant will increase and the survival rates will improve.
Virologically compromised donor grafts in liver transplantation.
The use of so-called ‘marginal donors’, such as older donors, those with increased steatosis, and donors with evidence of prior exposure to hepatitis B or C viruses, has increased, resulting in the development of more efficacious treatment modalities.
2018 Annual Report of the European Liver Transplant Registry (ELTR) – 50‐year evolution of liver transplantation
  • R. Adam, V. Karam, +41 authors C. Duvoux
  • Medicine
    Transplant international : official journal of the European Society for Organ Transplantation
  • 2018
An overview of trends and results of liver transplantation in Europe from 1968 to 2016 is provided, as well as information on evolution of techniques, and outcomes in LT in Europe over more than five decades is provided.
Liver Transplantation: Surgical Aspects
Liver transplantation (LT) is now a well-accepted treatment method for end-stage liver disease and acute liver failure. It is also one of the most expensive treatments. With the advances in technical
Liver Transplantation for Alcoholic Liver Disease in Europe: A Study from the ELTR (European Liver Transplant Registry)
  • P. Burra, M. Senzolo, +4 authors J. Neuberger
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2010
Outcome after LT for ALD cirrhosis has a favorable outcome, however, hepatitis C virus co‐infection seems to eliminate this advantage, so screening for de novo tumors and prevention of cardiovascular complications are essential to provide better long‐term results.


Quality control of transplant registries
An analysis of quality of data recorded in the European Liver Transplant Registry indicates that the scientific data held in the EU Registry is of a high quality and therefore of very considerable value in analyzing the indications for and outcomes of liver transplantation in Europe.
Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study
The normalised intrinsic mortality risk can be combined with the relative risk ratios of known risk factors to better estimate the mortality risk of a given procedure in a given patient.
Quality control of the European Liver Transplant Registry: results of audit visits to the contributing centers
The results of audit visits indicate that ELTR data are reliable, and the scientific results of ELTR can be considered credible and representative of liver transplantation in Europe.
Liver surgery : operative techniques and avoidance of complications
This book covers not only descriptions of the various surgical procedures applicable to the liver and specific methods of transplantation, but also the possibilities offered by the various imaging procedures and the various methods of transecting parenchyma.
Assessing the quality of the data in a transplant registry: the European Liver Transplant Registry.
Data quality assurance should start with deciding in advance the uses to which the database is going to be put, developing an explicitly defined minimum data set, and setting up a user-friendly interface.
Reliability of voluntary and compulsory databases and registries in the United States.
In the United States, there are several transplant registries and databases that contribute significantly to the scientific analyses of transplant outcomes and complications and provide important data through publications and presentations that can improve patient care and influence local, regional, and national transplant policies.