Evolution of liver transplantation in Europe: Report of the European Liver Transplant Registry

@article{Adam2003EvolutionOL,
  title={Evolution of liver transplantation in Europe: Report of the European Liver Transplant Registry},
  author={Ren{\'e} Adam and Paul Mcmaster and John G O'grady and Denis Castaing and J{\"u}rgen Klempnauer and Neville V. Jamieson and Peter Neuhaus and Jan Lerut and Mauro Salizzoni and Stephen G. Pollard and Ferdinand Muhlbacher and Xavier Rogiers and Juan Carlos Garcia Valdecasas and Joaqu{\'i}n Berenguer and Daniel Jaeck and Enrique Moreno Gonz{\'a}lez},
  journal={Liver Transplantation},
  year={2003},
  volume={9}
}
The European Liver Transplant Registry (ELTR) currently allows for the analysis of 44,286 liver transplantations (LTs) performed on 39,196 patients in a 13‐year period. After an exponential increase, the number of LTs is plateauing due to a lack of organs. To cope with this, alternatives to cadaveric LT, such as split LT, domino LT, or living‐related LT (LRLT) are being used increasingly. They now account for 11% of all procedures. One of the most important findings in the evolution of LT is… 
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References

SHOWING 1-6 OF 6 REFERENCES
Quality control of transplant registries
TLDR
An analysis of quality of data recorded in the European Liver Transplant Registry indicates that the scientific data held in the EU Registry is of a high quality and therefore of very considerable value in analyzing the indications for and outcomes of liver transplantation in Europe.
Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study
TLDR
The normalised intrinsic mortality risk can be combined with the relative risk ratios of known risk factors to better estimate the mortality risk of a given procedure in a given patient.
Quality control of the European Liver Transplant Registry: results of audit visits to the contributing centers
TLDR
The results of audit visits indicate that ELTR data are reliable, and the scientific results of ELTR can be considered credible and representative of liver transplantation in Europe.
Liver surgery : operative techniques and avoidance of complications
TLDR
This book covers not only descriptions of the various surgical procedures applicable to the liver and specific methods of transplantation, but also the possibilities offered by the various imaging procedures and the various methods of transecting parenchyma.
Assessing the quality of the data in a transplant registry: the European Liver Transplant Registry.
TLDR
Data quality assurance should start with deciding in advance the uses to which the database is going to be put, developing an explicitly defined minimum data set, and setting up a user-friendly interface.
Reliability of voluntary and compulsory databases and registries in the United States.
TLDR
In the United States, there are several transplant registries and databases that contribute significantly to the scientific analyses of transplant outcomes and complications and provide important data through publications and presentations that can improve patient care and influence local, regional, and national transplant policies.