Evolution of ligand specificity in vertebrate corticosteroid receptors

@inproceedings{Arterbery2010EvolutionOL,
  title={Evolution of ligand specificity in vertebrate corticosteroid receptors},
  author={Adam Starr Arterbery and Daniel J. Fergus and Elizabeth A. Fogarty and John K Mayberry and David L Deitcher and W Lee Kraus and Andrew H Bass},
  booktitle={BMC Evolutionary Biology},
  year={2010}
}
BackgroundCorticosteroid receptors include mineralocorticoid (MR) and glucocorticoid (GR) receptors. Teleost fishes have a single MR and duplicate GRs that show variable sensitivities to mineralocorticoids and glucocorticoids. How these receptors compare functionally to tetrapod MR and GR, and the evolutionary significance of maintaining two GRs, remains unclear.ResultsWe used up to seven steroids (including aldosterone, cortisol and 11-deoxycorticosterone [DOC]) to compare the ligand… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 22 CITATIONS

Corticosteroid receptor gene expression is related to sex and social behaviour in a social fish.

  • Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
  • 2013
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 58 REFERENCES

Evolution of the corticosteroid receptor signalling pathway in fish.

  • General and comparative endocrinology
  • 2007
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Evidence for two distinct functional glucocorticoid receptors in teleost fish

NR Bury, A Sturm, +7 authors P Prunet
  • J Mol Endocrinol
  • 2003
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Comparative vertebrate endocrinology

VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL