Evolution of innate and adaptive effector cell functions during acute HIV-1 infection.

@article{Alter2007EvolutionOI,
  title={Evolution of innate and adaptive effector cell functions during acute HIV-1 infection.},
  author={Galit Alter and Nickolas Teigen and Ryan W Ahern and Hendrik Streeck and Angela Meier and E. S. Rosenberg and Marcus Altfeld},
  journal={The Journal of infectious diseases},
  year={2007},
  volume={195 10},
  pages={1452-60}
}
Early events during acute human immunodeficiency virus type 1 (HIV-1) infection are critical in determining the course of disease progression. Cells of the innate and adaptive immune responses are involved in this acute response to infection; however, little is known about the coevolution of innate and adaptive effector cell populations during the initial phase of HIV-1 infection. Here, we have characterized the development of innate natural killer (NK) cell and adaptive HIV-1-specific CD8(+) T… CONTINUE READING
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