Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates

Abstract

The genetically tractable model organism Caenorhabditis elegans was first used to model bacterial virulence in vivo a decade ago. Since then, great strides have been made in identifying the host response pathways that are involved in its defence against infection. Strikingly, C. elegans seems to detect, and respond to, infection without the involvement of… (More)
DOI: 10.1038/nri2689

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Cite this paper

@article{Irazoqui2010EvolutionOH, title={Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates}, author={Javier E Irazoqui and Jonathan M. Urbach and Frederick M. Ausubel}, journal={Nature Reviews Immunology}, year={2010}, volume={10}, pages={47-58} }