Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria.

Abstract

T lymphocytes and B lymphocytes are present in jawed vertebrates, including cartilaginous fishes, but not in jawless vertebrates or invertebrates. The origins of these lineages may be understood in terms of evolutionary changes in the structure and regulation of transcription factors that control lymphocyte development, such as PU.1. The identification and… (More)

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@article{Anderson2001EvolutionOH, title={Evolution of hematopoiesis: Three members of the PU.1 transcription factor family in a cartilaginous fish, Raja eglanteria.}, author={Michele K Anderson and X-J. Sun and Ann L. Miracle and Gary W. Litman and Ellen V Rothenberg}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2001}, volume={98 2}, pages={553-8} }