Evolution of deceased-donor transplantation in India with decline of commercial transplantation: a lesson for developing countries

  title={Evolution of deceased-donor transplantation in India with decline of commercial transplantation: a lesson for developing countries},
  author={Georgi Abraham and Yuvaram N. V. Reddy and Yogesh N.V. Reddy and Sunil S. Shroff and Milly Mathew and S. Saravanan},
  journal={Kidney International},
The positive impact of a structured deceased-donor program has resulted in a reduction in the number of commercial transplantation operations taking place in India. The engagement of private and government stakeholders has revealed the positive impact of deceased organ donation in India. The best example is the Tamil Nadu state model, where deceased donations have increased to 1.2 per million population compared to the national average of 0.08 per million population. In the last 30 months 994… 

Bold policy changes are needed to meet the need for organ transplantation in India

  • S. ShroffJ. Gill
  • Medicine, Political Science
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2021
The current status of organ transplantation in India is reviewed and new policies to establish a national organization to oversee deceased donor services in all states, to fund resources needed to support deceased donation, to leverage the existing living donor infrastructure to advance deceased donor transplantation and call for establishment of government policy on funding for post-transplant care and immunosuppression are proposed.

Establishing a deceased donor program in north Indian region: lessons learnt

The experience of establishing a new deceased donor program in the state of Uttar Pradesh in north India is described and a huge disparity between demand and supply of organs is described.

Overcoming roadblocks on the way to national self‐sufficiency: exploring the deceased donor potential in India

This issue of Transplant International, Kumar et al. have examined the potential for organ donation at a single public sector hospital in India and calculated donor numbers/per million population/year based on the current regional population.

Pakistan's experience with kidney transplantation and trade: a call for international solidarity.

It is equally important that transplant professionals and the governments of affluent countries consider measures to discourage, if not prevent, their citizens from travelling to impoverished countries such as Pakistan to buy organs.


The utility of number needed to treat (NNT) is demonstrated in ascertaining relative effectiveness of treatment modalities that would help to formulate appropriate healthcare policies.

Chronic kidney disease hotspots in developing countries in South Asia

The hotspots of CKD of undiagnosed etiology in South Asian countries including the North, Central and Eastern provinces of Sri Lanka and the coastal region of the state of Andhra Pradesh in India are described.



Evolution of renal transplantation in India over the last four decades

In India, there are only 3.25 renal transplantations done per million population from live and deceased donors, which is grossly inadequate. Efforts to improve deceased donation are also discussed in

Management of chronic allograft dysfunction by switch over to rapamycin.

  • V. SundaramG. Abraham V. Sathiah
  • Medicine
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
  • 2010
It is confirmed that rapamycin-based Immunosuppressive regimen improves renal function and graft survival with minimal side effects, in comparison to CNI-based immunosuppression.

Diagnostic efficacy of C4d immunostaining in the detection of the humoral component of renal allograft rejection and therapeutic implications.

C4d staining is a useful adjunct to routine histopathological methods in evaluating the humoral component of acute renal allograft dysfunction and helps in planning appropriate antirejection therapy with the goal of achieving long-term graft survival.

The incidence of end-stage renal disease in India: a population-based study.

This study provides the first population-based ESRD incidence data from India and reveals it to be higher than previously estimated, and Diabetic nephropathy is the leading cause of E SRD.

The Economics of Dialysis in India

It is estimated that by 2010, six million worldwide would need renal replacement therapy (RRT) costing 28 billion dollar, which would be a social calamity and an economic catastrophe.

The challenges of renal replacement therapy in Asia

  • G. Abraham
  • Medicine
    Nature Clinical Practice Nephrology
  • 2008